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Research progress on clinical hemostatic effect of hemocoagulase from Agkistrodon acutus

Haemocoagulase of Agkistrodon acutus for injection is a kind of protein hemostatic drug purified from the domestic venom of Agkistrodon acutus. The hemostatic mechanism of this drug is that after entering the body, the hemofibrinogen in the blood is cut off to make it become monomer fibrin, thus enhancing the blood coagulation function of the body The results of preclinical experiments showed that the drug could significantly shorten the bleeding time of tail clipping in mice and the clotting time of whole blood in rabbits Clinical studies have shown that it has a safe and effective hemostatic effect on abdominal, thyroid, obstetrics and gynecology, and urinary surgical incisions, but has no obvious hemostatic effect on chest surgical incisions


Post time: Nov-07-2022