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Treatment of mice with Agkistrodon acutus venom, locust snake venom, and anti snake venom serum_ Preliminary observation on ascitic carcinoma of EAC
[Abstract] This article reports that Agkistrodon acutus venom, Agkistrodon acutus venom, and anti snake venom serum can promote the vaccination of S_ (180). EAC ascites cancer mice significantly prolong survival time and reduce vaccination rates, but cannot completely prevent the growth of pain c...Read more -
Research progress and clinical application of drug components in snake venom
Snake venom has many bioactive components, mainly including protease and polypeptide It accounts for about 90%~95% of the dry weight of snake venom [l With the continuous development of technology, many biological protein active ingredients in snake venom are gradually It has been isolated and pu...Read more -
Antitumor invasion and metastasis of Agkistrodon acutus venom component ACTX-8 in southern Anhui Research on function
Objective To investigate the effect and phase of the component of Agkistrodon acutus venom ACTX-8 on the adhesion and invasion of cervical cancer cell Hela Shutdown system. Methods Fibronectin was coated in 96-well plate. Hela cells passed through 0, 2.5, 5, 10, 20, 40 g/ml of ACTX-8 After treatm...Read more -
snake venom
Snake venom is a liquid secreted by venomous snakes from their venomous glands. Its main component is toxic protein, accounting for 90% to 95% of the dry weight. There are about 20 kinds of enzymes and toxins. In addition, it also contains some small molecular peptides, amino acids, carbohydrates...Read more -
Research progress and clinical significance of drug components in snake venom
Defibrase is currently approved by the State Food and Drug Administration For clinical application, it is derived from Agkistrodon acutus (Atracter acutus, known as Ar Agkistrodon halys Pallas (Gf0, Bilin 6I! D, secreted at the exit of Lisi) ¨ “, mainly used for acute cerebral embolism The ...Read more -
Preparation of Agkistrodon acutus venom
The venom of Agkistrodon acutus (also known as Agkistrodon acutus) is extracted by pinching the nose and squeezing, and added with 5O for Chinese herbal medicine such as wolfberry. It is made by soaking, processing and purifying grain Baijiu. Blended into Agkistrodon acutus venom has the function...Read more -
Main biological characteristics of Agkistrodon acutus
Agkistrodon halys is also known as Agkistrodon acutus, Agkistrodon acutus, White Snake, Chessboard Snake, Silk Snake, Baibu Snake, Lazy Snake, Snaker, Big White Snake, etc. It is a famous snake unique to China. Morphological characteristics: The snake is large, with a body length of 2 meters, or ...Read more -
Separation of anticoagulant and fibrinolytic components from Agkistrodon acutus venom and its effect on blood coagulation system
[Abstract] Objective: To study the effect of thrombin-like and fibrinolytic enzymes isolated and purified from the same Agkistrodon acutus venom on the blood coagulation system. Methods: The thrombin-like and fibrinolytic enzymes were isolated and purified from Agkistrodon acutus venom by DEAE-Se...Read more -
Inhibitory effect of antitumor component I from Agkistrodon acutus venom on proliferation of human lung cancer A549 cells
[Abstract] Objective: To study the effect of Agkistrodon acutus venom tumor suppressor component I (AAVC-I) on the proliferation inhibition and apoptosis of human lung cancer A549 cells. Methods: The inhibition rates of AAVC-I at different concentrations on A549 cells for 24h and 48h were measure...Read more -
Inhibitory effect of antitumor component I of Agkistrodon halys venom on proliferation of human lung cancer A549 cells
[Abstract] Objective: To study the effect of Agkistrodon acutus venom tumor suppressor component I (AAVC-I) on the proliferation inhibition and apoptosis of human lung cancer A549 cells. Methods: The inhibition rates of AAVC-I at different concentrations on A549 cells for 24h and 48h were measure...Read more -
Study on thrombosis of anticoagulant components from Agkistrodon acutus venom
[Abstract] In this paper, the effects of the anticoagulant component of Agkistrodon acutus venom on thrombosis and thrombin time were studied. The results showed that this component could shorten thrombin time, and the thrombus formed after this component was coagulated. Soluble in 30% urea solut...Read more -
Study on Three-dimensional Fluorescence Spectra of Agkistrodon acutus Hemorrhagic Toxin Ⅲ
[Abstract] Snake venom contains a variety of metal proteins, which have different biological activities, such as anticoagulant factor (ACF), glycoside hydrolase (NADase), fibrinolytic component (FP) and haemorrhagic toxin. Studies on their biological activities, fluorescence spectra and structura...Read more